Trastuzumab相关论文
Bispecific antibody simultaneously targeting PD1 and HER2 inhibits tumor growth via direct tumor cel
Immune checkpoint blockade has shown significant clinical benefit in multiple cancer indications,but many patients are e......
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Cardiac safety of the adjuvant Trastuzumab in Chong Qing population:monocentric study of about 267 H
Objective Background and Objective: Trastuzumab adjuvant therapy remarkable improves the prognosis of breast cancer pati......
Circulating tumor DNA analyses predict progressive disease and indicate trastuzumab-resistant mechan
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The Effect of Recombinant Human Endostatin Combined by Trastuzumab on Her-2 Positive Breast Cancer:a
Objective In this study,we aimed to investigate the combined effect of Trastuzumab plus recombinant human Endostatin(rh-......
Loss of HER2 positivity after anti-HER2 chemotherapy in HER2-positive gastric cancer patients: Resul
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Efficacy and prognostic factors of trastuzumab based therapy in HER2 positive advanced gastric cance
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The ErbB2-overexpression tumor metastasis suppression by humanized antibody chA21 with new recogniti
It is widely known that ErbB2 (HER2/p185her2/neu) overexpression in human malignant cancers correlates with poor prognos......
Evaluation of HER2 expression after chemotherapy with Trastuzumab in patients with Conversion Surger
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目的 表皮生长因子受体(EGFR)家族(包括EGFR、HER2、HER3、HER4)广泛存在于体内各种细胞中,其异常活化与多种人类上皮瘤的发生、发......
Targeted Micellar Phthalocyanine for Lymph Node Metastasis Homing and Photothermal Therapy in an Ort
Tumor lymph node(LN)metastasis seriously affects the treatment prognosis.Studies have shown that nanoparticles with size......
Targeted Micellar Phthalocyanine for Lymph Node Metastasis Homing and Photothermal Therapy in an Ort
Tumor lymph node (LN) metastasis seriously affects the treatment prognosis. Studies have shown that nanoparticles with s......
目的 探讨紫杉醇联合曲妥珠单抗治疗表皮生长因子受体-2( Her-2)阳性可手术乳腺癌的临床疗效及其安全性.方法 22例Her-2阳性浸润性......
目的：探讨曲妥珠单抗在治疗HER-2高表达的胃癌患者中出现的毒副作用及采取的护理措施。方法使用曲妥珠单抗前对患者进行全面评估，准......
目的 探讨曲妥珠单抗联合长春瑞滨在人表皮生长因子受体2(HER-2)阳性晚期乳腺癌患者中的治疗效果.方法 选择2010年4月至2013年4月9......
Maintenance treatment of trastuzumab for patients with advanced breast cancer to achieve long term s
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Objective:To assess the long-term effectiveness and safety of trastuzumab in adjuvant therapy for Chinese patients with ......
人表皮生长因子受体-2 (Her-2)是一种具有酪氨酸激酶活性的185 000的跨膜糖蛋白,在细胞分裂增殖信号跨膜转导中发挥重要功能,最终......
采用ELISA法建立检测恒河猴血清中trastuzumab的酶联免疫竞争法,为研究人体内trastuzumab的药物动力学学和药效学提供依据。方法的......
1商品名Hercetin2开发与上市厂商（美）Genentech公司研制并于1998年6月首次在美国上市。3药效分类免疫激动剂4药理本品是一种重组“人......
目的探讨曲妥珠单抗联合不同化疗方案治疗人表皮生子因子受体2(Her-2)阳性晚期乳腺癌的疗效和安全性。方法选取2013年1月—2015年1......
We present a 29-year-old woman with pT2N0M0 breast cancer, histological diagnosis of invasive ductal carcinoma, ER and P......
@@HER-2是细胞表皮生长因子受体家族的一员，它的活化会级联激活胞内RA5IRAFIMAPK途径，因此HER-2阳性乳腺癌靶向治疗主要包括HER-2单......
会议
Protein Tyrosine Phosphatase SHP-1 Sensitizes EGFR/HER-2 Positive Breast Cancer Cells to Trastuzumab
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分子靶向治疗具有特异性强、效果显著、不良反应小等特点，现已成为人表皮生长因子受体2（HER－2）阳性乳腺癌治疗的重要手段。随着抗 HER－2......
目前尚无多西他赛与长春瑞滨治疗早期乳腺癌效果的比较。HER-2阳性患者给予化疗联合短期曲妥珠单克隆抗体辅助治疗的疗效和长期安......
Summary: To study the effect of Trastuzumab in combination with IFN α-2b on HER2 and MRP1 of ACHN in vitro, ACHN cell l......
采用ELISA法建立检测恒河猴血清中trastuzumab的酶联免疫竞争法,为研究人体内trastuzumab的药物动力学学和药效学提供依据.方法的......
期刊
Human epidermal growth factor receptor 2(HER2)is over-expressed in 20%-25% of invasive breast cancer and is associated w......
Effect of trastuzumab combined with paclitaxel neoadjuvant chemotherapy on the cell proliferation an
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Effect of Trastuzumab on the Micellization Properties, Endocytic Pathways and Antitumor Activities o
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的：探讨人表皮生长因子受体3（human epidermal growth factor receptor-3，HER3）在人表皮生长因子受体2（human epidermal growth facto......
曲妥珠单抗在治疗人类表皮生长因子受体2 (Her-2)过表达的乳腺癌患者中存在耐药现象,其耐药的可能机制包括曲妥珠单抗与Her-2受体......
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目的:探析乳腺癌患者曲妥珠单抗治疗中应用细节管理护理的临床效果。方法:纳入2017年1月至2019年12月常州市肿瘤医院收治的80例乳......
Pancreaticoduodenectomy after neoadjuvant chemotherapy for gastric cancer invading the pancreatic he
BACKGROUND Pancreaticoduodenectomy(PD)for advanced gastric cancer is rarely performed because of the high morbidity and ......
乳腺癌是危害女性健康的恶性肿瘤疾病,发病率呈逐年上升趋势。HER2+乳腺癌由于侵袭性高,且预后质量差,一直是临床研究的重点。曲妥......
目的探讨HER2阳性乳腺癌患者应用曲妥珠单抗联合顺铂化学治疗的临床疗效及对远期生存的影响。方法选择76例行乳腺癌改良根治术的HE......
目的探讨曲妥珠单抗对人表皮生长因子受体2(HER2)阳性Ⅳ期乳腺癌的治疗效果及患者预后的影响因素。方法收集229例应用曲妥珠单抗治......
目的该研究旨在探讨Trastuzumab修饰四代聚酰胺-胺型枝状聚合物纳米粒对结肠癌SW480的靶向效果,为构建新型的靶向结肠癌的纳米递送......
目的该研究旨在探讨Trastuzumab修饰四代聚酰胺-胺型枝状聚合物纳米粒对结肠癌SW480的靶向效果,为构建新型的靶向结肠癌的纳米递送......
目的分析术前应用曲妥珠单抗联合新辅助化疗对乳腺癌患者血清中血管新生因子及乳腺组织中凋亡相关分子的影响。方法选择2011年12月......
目的探讨曲妥珠单抗联合CAF化疗治疗晚期乳腺癌临床效果。方法选取自2012年1月至2015年2月武汉大学人民医院收治的132例晚期乳腺癌......
进展胃癌患者往往失去手术等根治性治疗的机会;但目前西妥昔单抗（Cetuximab）、贝伐单抗（Bevacizumab）等分子靶向药物对胃癌极不敏感,仅......
曲妥珠单抗是针对Her2阳性乳腺癌的分子靶向药物,该文报道1例在单用曲妥珠单抗（每3周1次）方案治疗后出现左心室功能不全的右乳腺癌患......
目的:探讨HER-2在结肠癌中的表达情况及体外抗HER-2治疗对结肠癌细胞生物学活性的影响。方法:培养5株结肠癌细胞,RT-PCR法检测各株......
